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memantine.com - Memantine in moderate-to-severe Alzheimer's Disease
Memantine in moderate-to-severe Alzheimer's disease ... Patients with moderate-to-severe Alzheimer's disease were randomly assigned to ...
memantine.com - Memantine in moderate-to-severe Alzheimer's Disease
... of memantine in patients suffering from moderate to severe Alzheimer dementia. ... The memantine-treated patients showed significantly less decline in cognitive ...
Memantine Helpful in Moderate-to-Severe Alzheimer's Disease
Memantine Helpful in Moderate-to-Severe Alzheimer's Disease CME. Disclosures ... Discuss the effects of memantine in moderate-to-severe Alzheimer's disease. ...
Memantine in Moderate-to-Severe Alzheimer's Disease -- Research article ...
This New England Journal of Medicine study concludes antiglutamatergic treatment with memantine, an NMDA antagonist, reduced clinical deterioration in moderate-to ...
030403 Memantine in Moderate-to-Severe Alzheimer's Disease
... treatment reduced clinical deterioration in moderate-to-severe ... memantine in outpatients with moderate-to-severe. Alzheimer's disease. p a t i e n t s ...
Facts:
effectiveness of memantine in treating moderate to severe Alzheimer's disease: ... drug application seeking approval of memantine for moderate to severe disease. ...
Memantine in moderate-to-severe Alzheimer's disease.
METHODS: Patients with moderate-to-severe Alzheimer's disease were randomly ... reduced clinical deterioration in moderate-to-severe Alzheimer's disease, a ...
STEPS - March 15, 2004 - American Family Physician
Memantine (Namenda) for Moderate to Severe Alzheimer's Disease ... Memantine in moderate-to-severe Alzheimer's disease. N Engl J Med 2003;348:1333-41. ...
memantine (Namenda) - drug class, medical uses, medication side effects ...
Specifies the medication memantine (Namenda), a drug used for the treatment of moderate to severe dementia of the Alzheimer's type.
Fact Sheet: About Memantine
effectiveness of memantine in treating moderate to severe Alzheimer's disease: ... moderate to severe disease by the end of 2003. How is memantine supplied and ...
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Memantine in moderate to severe |
Efficacy and Safety of Memantine in Moderate to Severe Alzheimer's Disease - Full Text View - ClinicalTrials.gov
First Received: March 5, 2009
Last Updated: April 16, 2009
History of Changes
The secondary objectives are to evaluate the efficacy of memantine on global condition, functioning, quality of life, resource utilisation, safety and
tolerability. [ Time Frame: 6 months ] [ Designated as safety issue: Yes ]Memantine is a moderate affinity, uncompetitive NMDA receptor antagonist. Pre-clinical studies have demonstrated that memantine can decrease the neuronal toxicity associated with excessive glutamate release and calcium overload in neurons. Results from clinical trials in patients with moderate to severe Alzheimer's Disease (AD) have demonstrated memantine's efficacy and safety by showing positive treatment effects on cognitive, global and functional decline.
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Rating: 3.5 из 5 (голосов: 151) |
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24 october 2008
Николай Лобецкий
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