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Actual
Namenda (Memantine), Alzheimer's medication
Namenda (Memantine)is a medication used in the treatment of Alzheimer's. ... a combination of memantine and donepezil was similar to that of donepezil alone. ...

Donepezil - Wikipedia, the free encyclopedia
Donepezil is sometimes used[citation needed] in combination with memantine, a ... Memantine to stable donepezil therapy improves cognition, functioning and ...

Memantine Plus Donepezil for Alzheimer's Disease - May 1, 2004 ...
... Is the combination of memantine and donepezil effective in the treatment of Alzheimer's disease? ... and safety of memantine combined with donepezil, a ...

memantine.com - Combination of Memantine with Acetylcholinesterase ...
... treated with memantine/ donepezil and the placebo-/ donepezil combination. ... Memantine treatment in patients already receiving Donepezil. Tariot et al. (2004) ...

Memantine Helpful in Alzheimer's Disease
In a randomized trial, patients taking donepezil for moderate to severe AD benefitted from the addition of this NMDA receptor antagonist.

Donepezil: Information from Answers.com
... formula: Drug Forms: Donepezil Hydrochloride Oral solution (below) Donepezil ... Memantine to stable donepezil therapy improves cognition, functioning and ...

News - Memantine Adds Benefits to Donepezil Therapy in Alzheimer's ...
Memantine Adds Benefits to Donepezil Therapy in Alzheimer's Patients: Presented at AGS ... in the US examined safety and efficacy of memantine for 24 weeks. ...

memantine.com - Effects of memantine and donepezil on amyloid beta ...
Effects of memantine and donepezil on amyloid beta-induced memory impairment in ... clinical data showing that memantine and donepezil are effective for the ...

Memantine - Wikipedia, the free encyclopedia
Memantine is marketed under the brands Axura and Akatinol by Merz, Namenda by ... guidance 111 Donepezil, galantamine, rivastigmine (review) and memantine for the ...

Donepezil and Memantine in Moderate to Severe Alzheimer's Disease ...
Donepezil and Memantine in Moderate to Severe Alzheimer's Disease (DOMINO-AD) ... given the combination of memantine and donepezil at the point of transition ...

Memantine and donepezil

memantine and donepezil news item - Memantine and donepezil combination in severe Alzheimer's diseaseA placebo-controlled clinical trial in patients with moderate to severe Alzheimer's disease (AD) suggests that memantine can add some benefit to existing treatment with donepezil. It involved 404 patients already stabilised on donepezil, who were given memantine or placebo daily for 24 weeks. Assessment was using a number of standard outcome measures for dementia, and 322 (80%) of patients completed the trial. The results favoured memantine over placebo for all measures, and the authors conclude that adding memantine to stable donepezil treatment gave significantly better outcomes than placebo. [Editor's comment: although a 20% dropout rate may seem quite high, it is probably not unreasonable for this group of patients. The changes in outcomes are statistically significant, but it's not clear whether they represent clinically significant improvements in functioning.



Rating: 3.5 из 5 (голосов: 151)

7 october 2008
Сергей Чебурекин

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