Namenda (Memantine), Alzheimer's medication
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Alzheimer Treatment: Ebixa, Memantine Hydrochloride
Information from the Alzheimer Society of Canada on drug treatments for Alzheimer's disease available in Canada, plus updates on Canadian drug trials.
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PATIENT INSTRUCTIONS FOR NAMENDA
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Alzheimer Treatment: Ebixa, Memantine Hydrochloride (also
known as memantine hydrochloride) Ebixa
has been conditionally approved* by
Health Canada to relieve the symptoms of people with
moderate to severe Alzheimer's disease. It has been approved
pending the results of further studies to verify its
clinical benefit.Ebixa is one of a group of drugs called NMDA (N-methyl-D-aspartate) receptor antagonists. Receptors are
molecules on cells which receive other molecules, so allowing those molecules to initiate important chemical
reactions. The NMDA receptors are the receiving targets of glutamate molecules released from nerves; when
these molecules interact with NMDA receptors they function as neurotransmitters , passing on messages
from one nerve cell to another. In a disease like Alzheimer's disease, nerve cells get sick and then massive
amounts of glutamate leak out of them. This excess of glutamate leads to excessive interaction with the NMDA
receptors.