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isotretinoin and Vibramycin monohydrate Drug Interactions
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CONTRAINDICATED: The use of vitamin A or related compounds (i.e., retinoids) with tetracyclines may increase the risk of pseudotumor cerebri, or benign intracranial hypertension. These agents individually have been associated with the development of pseudotumor cerebri and may have additive effects during coadministration. Specific reported cases of the potential interaction have involved the use of isotretinoin or vitamin A in combination with tetracyclines.