Nizoral Shampoo as a Hair Loss Treatment - Does it Work?Hair Loss Alopecia Information, Support, and Treatments Hair Systems Blogs Hair Systems Guide Hair Transplants Guide Transplant Blogs Wigs, Toppers Extensions "Started noticing my hair thinning out from front to back. Just got provillus. seeing what other people on here are using and whats working out for them. Looking to slow down my hair los..." Nizoral is primarily an antifungal shampoo that also has androgen blocking properties. This makes it an effective anti-inflammatory for hair loss sufferers. What is an androgen blocker? The most well known Androgen Blocker is Topical Spironolactone for Men and Women. Hair thins because of hormone activity in your scalp. Androgen blockers inhibit those processes. Left unchecked, inflammation takes over. Many people who start losing hair have itching, tingling, and intense irritation and even pain in their scalp.