Nizoral tablets (ketoconazole)Complementary health practitionersNizoral tablets contain the active ingredient ketoconazole, which is a type of medicine called an antifungal. It is used to treat infections with fungi and yeasts. Ketoconazole kills fungi and yeasts by interfering with their cell membranes. It works by stopping the fungi from producing a substance called ergosterol, which is an essential component of fungal cell membranes. The disruption in production of ergosterol disrupts the fungal cell membrane, causing holes to appear in it. When ketoconazole is taken by mouth it may very rarely have serious side effects on the liver. For this reason, your doctor will want to check your liver function before your treatment is started and monitor your liver function regularly during the treatment. This will involve a blood test before starting the tablets, and further blood tests after two weeks, four weeks and then every month until your treatment is finished. You should tell your doctor immediately if you experience any symptoms of a liver problem during treatment. Symptoms that may suggest a liver problem include persistent nausea and vomiting, unexplained itching, abdominal pain, loss of appetite, fatigue, dark urine or the development of jaundice (a yellow colouring to the skin and the whites of the eyes).