Doryx and birth
Doxycycline (Doryx) Facts - eMedExpert.comFioricet (Butalbital/ Acetaminophen/ Caffeine)The first member of the tetracycline group - Chlortetracycline - was discovered in the late 1940s by Dr. Benjamin Duggar of Lederle Laboratories in New York. It was derived from the soil-dwelling bacterium Streptomyces aureofaciens. Oxytetracycline was isolated soon after from S. rimosus by scientists at Pfizer Laboratories in 1950. This was further developed to Doxycycline Doxycycline is generally bacteriostatic against a wide variety of organisms, both gram-positive and gram-negative. In gram-negative bacteria, transportation of the drug into the cell occurs either by passive diffusion or through an energy-dependent active transport system. The latter system is also believed to exist in gram-positive bacteria. Doxycycline and minocycline are more lipophilic than the other tetracyclines, which allows them to pass easily through the lipid bilayer of bacteria.