Bactroban Cream Official FDA information, side effects and uses. A B C D E F G H I J K L M N O P Q R S T U V W X Y Z Bactroban Cream (mupirocin calcium cream), 2% contains the dihydrate crystalline calcium hemi-salt of the antibiotic mupirocin. Chemically, it is ( E,2S,3R,4R,5S) - 5 - [(2S,3S,4S,5S) - 2,3 - Epoxy - 5 - hydroxy - 4 - methylhexyl]tetrahydro - 3,4 - dihydroxy - - methyl - 2H - pyran - 2 - crotonic acid, ester with 9-hydroxynonanoic acid, calcium salt (2:1), dihydrate. in area) in 16 adults (aged 29 to 60 years) and 10 children (aged 3 to 12 years). Some systemic absorption was observed as evidenced by the detection of the metabolite, monic acid, in urine. Data from this study indicated more frequent occurrence of percutaneous absorption in children (90% of patients) compared to adults (44% of patients); however, the observed urinary concentrations in children (0.07 - 1.3 mcg/mL [1 pediatric patient had no detectable level]) are within the observed range (0.08 - 10.03 mcg/mL [9 adults had no detectable level]) in the adult population. In general, the degree of percutaneous absorption following multiple dosing appears to be minimal in adults and children. Any mupirocin reaching the systemic circulation is rapidly metabolized, predominantly to inactive monic acid, which is eliminated by renal excretion.
BACTROBAN CREAM USAGE
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