Inhouse Pharmacy (UK) impetigo, a bacterial infection of the skin treated with Bactroban, Mupirocin Ointment 2If the use of Bactroban does not clear your skin infection within 3 to 5 days, or if the infection becomes worse, notify your doctor.The effects of Bactroban during pregnancy have not been adequately studied. If you are pregnant or plan to become pregnant, inform your doctor immediately. It is not known whether Bactroban appears in breast milk. Your doctor may advise you to discontinue breastfeeding until your treatment with this medication is finished.