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Moderate to Severe Eczema Treatment and Medication | Protopic.comThe product information provided on Protopic.com is intended for residents of the United States.Protopic is the only TCI indicated for moderate to severe eczema. Since approval by the Food and Drug Administration (FDA) in December 2000, an estimated 2.1 million patients in the United States and 5.4 million patients worldwide have been treated with Protopic.