Prograf - Tacrolimus - Dosage - Side Effects - Drug Interactions - WarningsPrograf (tacrolimus) drug information, dosage, side effects, drug interactions, and warnings. Prograf, generic drug name tacrolimus, is an immunosuppressive drug used to reduce rejection of organ or bone marrow transplants. Tacrolimus is also approved for treating skin conditions such as eczema (atopic dermatitis) and psoriasis.