MedlinePlus Drug Information: Lithium A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 0-9 Lithium comes as a tablet, capsule, extended-release (long-acting) tablet, and solution (liquid) to take by mouth. The tablets, capsules, and solution are usually taken three to four times a day.The extended-release tablets are usually taken two to three times a day. Take lithium at around the same times every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take lithium exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take.