PRIADEL, Lithium carbonate, Priadel 400 mg prolonged releas, Medicine and Disease informationBy viewing the content of this web page you are both confirming your status as a healthcare professional and agreeing to our terms of use. Priadel: White, circular, bi-convex tablets engraved PRIADEL on one side, scored on the other side, in a prolonged release formulation. Priadel 200: White, scored, capsule-shaped tablets engraved P200 on one side, in a prolonged release formulation. A simple treatment schedule has been evolved which except for some minor variations should be followed whether using Priadel therapeutically or prophylactically. The minor variations to this schedule depend on the elements of the illness being treated and these are described later. 1. In patients of average weight (70kg) an initial dose of 400-1,200mg of Priadel may be given as a single daily dose in the morning or on retiring. Alternatively, the dose may be divided and given morning and evening. The tablets should not be crushed or chewed. When changing between lithium preparations serum lithium levels should first be checked, then Priadel therapy commenced at a daily dose as close as possible to the dose of the other form of lithium. As bioavailability varies from product to product (particularly with regard to retard or slow release preparations) a change of product should be regarded as initiation of new treatment. 2. Four to five days after starting treatment (and never longer than one week) a blood sample should be taken for the estimation of serum lithium level. 3. The objective is to adjust the Priadel dose so as to maintain the “Target” serum lithium concentrations at 12 and 24 hours as shown in the table below. “Target” serum lithium concentration (mmol/l) At 12 hours Once daily dosage 0.7 – 1.0, 0.5 – 0.8 At 24 hours Twice daily dosage 0.5 – 0.