Galantamine : by Ray Sahelian, M.D., galantamine for alzheimer'sGalantamine supplement information by Ray Sahelian, M.D. Health benefit and side effects of galantamineGalantamine is a cholinergic medicine. Galantamine can be isolated from several plants, including daffodil bulbs, but is now synthesized. Galantamine is available over the counter and also by prescription. Galantamine offsets reductions in central cholinergic neurotransmission in Alzheimer's disease by specifically and reversibly inhibiting the acetylcholinesterase enzyme. This allows more acetylcholine to be available in the brain. Galantamine is also a nicotinic receptor agonist. Another herbal extract that has potential in the therapy of Alzheimer's disease is Huperzine A.