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Alzforum: Drugs In Clinical Trials - DonepezilHomeContact UsHow to CiteGet NewsletterBecome a MemberLogin The Forum does not endorse any medical product or therapy. ALL medications and supplements should be taken ONLY under the supervision of a physician, due to the possibility of side-effects, drug interactions, etc. Donepezil is contraindicated in patients with known hypersensitivity to the drug or to other piperidine derivatives. Should be prescribed with caution to patients with sick-sinus syndrome or other cardiac conduction abnormalities, asthma, seizures, active gastrointestinal disease, or in patients receiving non-steroidal antiinflammatory agents.