Bactroban Cream - Drug information from MediLexicon Abbreviations Abbrev Definitions Dictionary ICD9 Codes Equipment Hospitals Drugs More.. Bactroban Cream (mupirocin calcium cream, 2%) has been approved as a topical antibiotic treatment for secondarily infected traumatic skin lesions. Bactroban Cream will be available in 15 gram and 30 gram tubes. Bactroban Cream should be applied to the affected area three times daily for 10 days.