BACTROBAN TOPICAL (ointment) BACTROBAN TOPICAL (ointment)Mupirocin is an antibiotic produced through fermentation of Mupirocin has bacteriostatic properties at minimum inhibitory concentrations and bactericidal properties at the higher concentrations reached when applied locally. Polyethylene glycol can be absorbed from open wounds, burns and damaged skin and is excreted by the kidneys. BACTROBAN TOPICAL ointment should not be used in conditions where absorption of large quantities of polyethylene glycol is possible: especially if there is evidence of moderate or severe renal impairment. The excretion of polyethylene glycol may be impaired and could lead to nephrotoxicity and severe metabolic disturbances.