BACTROBAN OINTMENT MUPIROCIN

mupirocin, mupirocin calcium (Bactroban, Bactroban Nasal, Centany) Drug Information on MedicineNet.com Mupirocin is an antibiotic that is used topically (on the skin) for the treatment of impetigo, a bacterial disease of the skin caused by Unlike most other antibiotics which act on either bacterial DNA or the walls of bacteria, mupirocin blocks the activity of an enzyme called isoleucyl-tRNA synthetase within the bacteria. This enzyme is necessary in order for the bacteria to make proteins. Without the ability to make proteins, the bacteria die. Because of its unique mechanism of action, there is little chance that bacteria will have become resistant to mupirocin because of exposure to other antibiotics. Mupirocin topical cream was approved by the FDA in December 1987. The intranasal form was approved in October 1995.